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Extension of chemotactic pseudopods by nonadherent human neutrophils does not require or cause calcium bursts

Global bursts in free intracellular calcium (Ca(2+)) are among the most conspicuous signaling events in immune cells. To test the common view that Ca(2+) bursts mediate rearrangement of the actin cytoskeleton in response to the activation of G protein–coupled receptors, we combined single-cell manip...

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Publicat a:Sci Signal
Autors principals: Francis, Emmet A., Heinrich, Volkmar
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053518/
https://ncbi.nlm.nih.gov/pubmed/29535263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aal4289
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