Vitamin A deficiency causes islet dysfunction by inducing islet stellate cell activation via cellular retinol binding protein 1

Background: Vitamin A (VA) plays an essential role in pancreatic homeostasis. Islet stellate cells (ISCs) are VA-storing cells in pancreatic islets. Herein, we have investigated the effect of VA on glucose homeostasis trough regulation of ISCs function in dietary VA deficiency model mice. Methods: M...

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Udgivet i:Int J Biol Sci
Main Authors: Zhou, Yunting, Zhou, Junming, Sun, Bo, Xu, Wei, Zhong, Ming, Li, Yumin, He, Cong, Chen, Yang, Wang, Xiaohang, Jones, Peter M, Sun, Zilin
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053333/
https://ncbi.nlm.nih.gov/pubmed/32140064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.37861
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