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A compact synthetic pathway rewires cancer signaling to therapeutic effector release
An important goal in synthetic biology is to engineer biochemical pathways to address unsolved biomedical problems. One long-standing problem in molecular medicine is the specific identification and ablation of cancer cells. Here, we describe a method named Rewiring of Aberrant Signaling to Effector...
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| Vydáno v: | Science |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053279/ https://ncbi.nlm.nih.gov/pubmed/31048459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat6982 |
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