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Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt

BACKGROUND: Many cancers arise from mutations in cells within epithelial tissues. Mutations manifesting at the subcellular level influence the structure and function of the tissue resulting in cancer. Previous work has proposed how cell level properties can lead to mutant cell invasion, but has not...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Romijn, Lotte B., Almet, Axel A., Tan, Chin Wee, Osborne, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053074/
https://ncbi.nlm.nih.gov/pubmed/32126976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3391-3
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