Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients

Rationale: Renal cell carcinoma (RCC) accounts for about 2% of all adult cancers, and clear cell RCC (ccRCC) is the most common RCC histologic subtype. A hallmark of ccRCC is the loss of the primary cilium, a cellular antenna that senses a wide variety of signals. Loss of this key organelle in ccRCC...

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Vydáno v:Theranostics
Hlavní autoři: Fabbri, Lucilla, Dufies, Maeva, Lacas-Gervais, Sandra, Gardie, Betty, Gad-Lapiteau, Sophie, Parola, Julien, Nottet, Nicolas, Meyenberg Cunha de Padua, Monique, Contenti, Julie, Borchiellini, Delphine, Ferrero, Jean-Marc, Leclercq, Nathalie Rioux, Ambrosetti, Damien, Mograbi, Baharia, Richard, Stéphane, Viotti, Julien, Chamorey, Emmanuel, Sadaghianloo, Nirvana, Rouleau, Matthieu, Craigen, William J., Mari, Bernard, Clavel, Stéphan, Pagès, Gilles, Pouysségur, Jacques, Bost, Frédéric, Mazure, Nathalie M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052902/
https://ncbi.nlm.nih.gov/pubmed/32194829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.41001
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