Valproic Acid and Epilepsy: From Molecular Mechanisms to Clinical Evidences

After more than a century from its discovery, valproic acid (VPA) still represents one of the most efficient antiepi-leptic drugs (AEDs). Pre and post-synaptic effects of VPA depend on a very broad spectrum of actions, including the regu-lation of ionic currents and the facilitation of GABAergic ove...

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Veröffentlicht in:Curr Neuropharmacol
Hauptverfasser: Romoli, Michele, Mazzocchetti, Petra, D’Alonzo, Renato, Siliquini, Sabrina, Rinaldi, Victoria Elisa, Verrotti, Alberto, Calabresi, Paolo, Costa, Cinzia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Science Publishers 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052829/
https://ncbi.nlm.nih.gov/pubmed/30592252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X17666181227165722
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