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BMPR2 dysfunction impairs insulin signaling and glucose homeostasis in cardiomyocytes

Insulin resistance and right ventricular (RV) dysfunction are associated with lipotoxicity in heritable forms of pulmonary arterial hypertension (PAH), commonly due to mutations in bone morphogenetic protein receptor type 2 (BMPR2). How BMPR2 dysfunction in cardiomyocytes alters glucose metabolism a...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Lung Cell Mol Physiol
Hoofdauteurs: Hemnes, Anna R., Fessel, Joshua P., Chen, Xinping, Zhu, Shijun, Fortune, Niki L., Jetter, Christopher, Freeman, Michael, Newman, John H., West, James D., Talati, Megha H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052666/
https://ncbi.nlm.nih.gov/pubmed/31850803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00555.2018
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