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How polypharmacologic is each chemogenomics library?

AIM: High-throughput phenotypic screens have emerged as a promising avenue for small-molecule drug discovery. The challenge faced in high-throughput phenotypic screens is target deconvolution once a small molecule hit is identified. Chemogenomics libraries have emerged as an important tool for meeti...

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Detalhes bibliográficos
Publicado no:Future Drug Discov
Main Authors: Ni, Eric, Kwon, Eehjoe, Young, Lauren M., Felsovalyi, Klara, Fuller, Jennifer, Cardozo, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Newlands Press Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052528/
https://ncbi.nlm.nih.gov/pubmed/32149277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fdd-2019-0032
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