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Deep graph embedding for prioritizing synergistic anticancer drug combinations

Drug combinations are frequently used for the treatment of cancer patients in order to increase efficacy, decrease adverse side effects, or overcome drug resistance. Given the enormous number of drug combinations, it is cost- and time-consuming to screen all possible drug pairs experimentally. Curre...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Jiang, Peiran, Huang, Shujun, Fu, Zhenyuan, Sun, Zexuan, Lakowski, Ted M., Hu, Pingzhao
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052513/
https://ncbi.nlm.nih.gov/pubmed/32153729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.02.006
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