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Metabolic response patterns in brain microdialysis fluids and serum during interstitial cisplatin treatment of high-grade glioma

BACKGROUND: High-grade gliomas are associated with poor prognosis. Tumour heterogeneity and invasiveness create challenges for effective treatment and use of systemically administrated drugs. Furthermore, lack of functional predictive response-assays based on drug efficacy complicates evaluation of...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Björkblom, Benny, Jonsson, Pär, Tabatabaei, Pedram, Bergström, Per, Johansson, Mikael, Asklund, Thomas, Bergenheim, A. Tommy, Antti, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052137/
https://ncbi.nlm.nih.gov/pubmed/31819184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0652-x
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