Covarying patterns of white matter lesions and cortical atrophy predict progression in early MS

OBJECTIVE: We applied longitudinal 3T MRI and advanced computational models in 2 independent cohorts of patients with early MS to investigate how white matter (WM) lesion distribution and cortical atrophy topographically interrelate and affect functional disability. METHODS: Clinical disability was...

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Vydáno v:Neurol Neuroimmunol Neuroinflamm
Hlavní autoři: Muthuraman, Muthuraman, Fleischer, Vinzenz, Kroth, Julia, Ciolac, Dumitru, Radetz, Angela, Koirala, Nabin, Gonzalez-Escamilla, Gabriel, Wiendl, Heinz, Meuth, Sven G., Zipp, Frauke, Groppa, Sergiu
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051213/
https://ncbi.nlm.nih.gov/pubmed/32024782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000681
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