Impaired Alanine Transport or Exposure to d-Cycloserine Increases the Susceptibility of MRSA to β-lactam Antibiotics

Prolonging the clinical effectiveness of β-lactams, which remain first-line antibiotics for many infections, is an important part of efforts to address antimicrobial resistance. We report here that inactivation of the predicted d-cycloserine (DCS) transporter gene cycA resensitized methicillin-resis...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Gallagher, Laura A, Shears, Rebecca K, Fingleton, Claire, Alvarez, Laura, Waters, Elaine M, Clarke, Jenny, Bricio-Moreno, Laura, Campbell, Christopher, Yadav, Akhilesh K, Razvi, Fareha, O’Neill, Eoghan, O’Neill, Alex J, Cava, Felipe, Fey, Paul D, Kadioglu, Aras, O’Gara, James P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050987/
https://ncbi.nlm.nih.gov/pubmed/31628459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz542
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