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Cyanine–Gemcitabine Conjugates as Targeted Theranostic Agents for Glioblastoma Tumor Cells

A small subset of heptamethine dyes (cyanine-7 or Cy7) share an intriguing characteristic: preferential tumor accumulation and retention. These dyes absorb in the near-infrared (NIR) region (above 750 nm) and perform active targeting to deliver therapeutic and toxic cargoes to various tumor models i...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Jiang, Zhengyang, Pflug, Kathryn, Usama, Syed Muhammad, Kuai, Dacheng, Yan, Xin, Sitcheran, Raquel, Burgess, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050787/
https://ncbi.nlm.nih.gov/pubmed/31469566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b01147
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