Serotonin Modulates AhR Activation by Interfering with CYP1A1-Mediated Clearance of AhR Ligands

BACKGROUND/AIMS: Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter and hormone with important physiological functions in many organs, including the intestine. We have previously shown that 5-HT activates the aryl hydrocarbon receptor (AhR) in intestinal epithelial cells (IECs) via a seroto...

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Vydáno v:Cell Physiol Biochem
Hlavní autoři: Manzella, Christopher R., Ackerman, Max, Singhal, Megha, Ticho, Alexander L., Ceh, Justin, Alrefai, Waddah A., Saksena, Seema, Dudeja, Pradeep K., Gill, Ravinder K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050772/
https://ncbi.nlm.nih.gov/pubmed/32017483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33594/000000209
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