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Humanized Mouse Models of Genetic Immune Disorders and Hematological Malignancies

The immune system is quite remarkable having both the ability to tolerate innocuous and self-antigens while possessing a robust capacity to recognize and eradicate infectious pathogens and foreign entities. The genetics that encode this delicate balancing act include multiple genes and specialized c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochem Pharmacol
Hauptverfasser: Tyagi, Rajeev K., Li, Jing, Jacobse, Justin, Snapper, Scott B., Shouval, Dror S., Goettel, Jeremy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050416/
https://ncbi.nlm.nih.gov/pubmed/31634456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2019.113671
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