Mediating role of bone marrow lesion, synovitis, pain sensitization, and depressive symptoms on knee pain improvement following substantial weight loss

OBJECTIVE. Massive weight loss leads to marked knee pain reduction in persons with knee pain, but the reason for the reduction in pain is unknown. To quantify the contribution of MRI changes in pain sensitive structures, bone marrow lesions (BML), synovitis, and in pain sensitization, or depressive...

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Bibliographic Details
Published in:Arthritis Rheumatol
Main Authors: Jafarzadeh, S. Reza, Neogi, Tuhina, Stefanik, Joshua J., Li, Jing-Sheng, Guermazi, Ali, Apovian, Caroline M., Felson, David T.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050338/
https://ncbi.nlm.nih.gov/pubmed/31562683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41125
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