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Nitrogen mustard exposure perturbs oocyte mitochondrial physiology and alters reproductive outcomes
Nitrogen mustard (NM) is an alkylating chemical warfare agent, and its derivatives are used in chemotherapy. Alkylating agents can cause mitochondrial damage, so exposed females may transmit damaged genomes to their children, since mitochondria are maternally inherited and oocytes are not thought to...
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| Publicado no: | Reprod Toxicol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7050192/ https://ncbi.nlm.nih.gov/pubmed/30308227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2018.10.002 |
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