Association of Circulating Vitamin D With Colorectal Cancer Depends on Vitamin D–Binding Protein Isoforms: A Pooled, Nested, Case-Control Study

BACKGROUND: Higher circulating 25-hydroxyvitamin-D [25(OH)D] concentrations are consistently inversely associated with colorectal cancer (CRC) risk in observational studies. However, it is unknown whether this association depends on the functional GC-rs4588*A (Thr436Lys) variant encoding the vitamin...

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Publicado no:JNCI Cancer Spectr
Main Authors: Gibbs, David Corley, Song, Mingyang, McCullough, Marjorie L, Um, Caroline Y, Bostick, Roberd M, Wu, Kana, Flanders, W Dana, Giovannucci, Edward, Jenab, Mazda, Brustad, Magritt, Tjønneland, Anne, Perez-Cornago, Aurora, Trichopoulou, Antonia, Tsilidis, Konstantinos K, Hultdin, Johan, Barricarte Gurrea, Aurelio, Bueno-de-Mesquita, Bas, Mahamat-Saleh, Yahya, Kühn, Tilman, Gunter, Marc J, Weiderpass, Elisabete, Fedirko, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050153/
https://ncbi.nlm.nih.gov/pubmed/32337495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pkz083
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