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Risk-Reducing Salpingo-Oophorectomy and Breast Cancer Risk Reduction in the Gynecologic Oncology Group Protocol-0199 (GOG-0199)

BACKGROUND: Risk-reducing salpingo-oophorectomy (RRSO) has been associated with approximately 50% breast cancer risk reduction among women with a pathogenic variant in BRCA1 or BRCA2 (BRCA1/2), a finding that has recently been questioned. METHODS: We estimated incidence rates of breast cancer and al...

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Veröffentlicht in:JNCI Cancer Spectr
Hauptverfasser: Mai, Phuong L, Miller, Austin, Gail, Mitchell H, Skates, Steven, Lu, Karen, Sherman, Mark E, Ioffe, Olga B, Rodriguez, Gustavo, Cohn, David E, Boggess, John, Rutherford, Thomas, Kauff, Noah D, Rader, Janet S, Phillips, Kelly-Anne, DiSilvestro, Paul A, Olawaiye, Alexander B, Ridgway, Mildred R, Greene, Mark H, Piedmonte, Marion, Walker, Joan L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050151/
https://ncbi.nlm.nih.gov/pubmed/32337492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pkz075
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