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Assessing Clinical Equivalence in Oncology Biosimilar Trials With Time-to-Event Outcomes

A typical biosimilar study in oncology uses the overall response evaluated at a specific time point as the primary endpoint, which is generally acceptable regulatorily, to assess clinical equivalence between a biosimilar and its reference product. The standard primary endpoint for evaluating an anti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:JNCI Cancer Spectr
Hauptverfasser: Uno, Hajime, Schrag, Deborah, Kim, Dae Hyun, Tang, Dejun, Tian, Lu, Rugo, Hope S, Wei, Lee-Jen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050006/
https://ncbi.nlm.nih.gov/pubmed/32337484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pkz058
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