Enhanced and Prolonged Antitumor Effect of Salinomycin-Loaded Gelatinase-Responsive Nanoparticles via Targeted Drug Delivery and Inhibition of Cervical Cancer Stem Cells

BACKGROUND: Cervical cancer stem cells (CCSCs) represent a subpopulation of tumor cells that possess self-renewal capacity and numerous intrinsic mechanisms of resistance to conventional chemotherapy and radiotherapy. These cells play a crucial role in relapse and metastasis of cervical cancer. Ther...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Wang, Qin, Liu, Fangcen, Wang, Lifeng, Xie, Chen, Wu, Puyuan, Du, Shiyao, Zhou, Shujuan, Sun, Zhichen, Liu, Qin, Yu, Lixia, Liu, Baorui, Li, Rutian
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049776/
https://ncbi.nlm.nih.gov/pubmed/32161458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S234679
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