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Enhancer–gene maps in the human and zebrafish genomes using evolutionary linkage conservation

The spatiotemporal expression of genes is controlled by enhancer sequences that bind transcription factors. Identifying the target genes of enhancers remains difficult because enhancers regulate gene expression over long genomic distances. To address this, we used an evolutionary approach to build t...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Clément, Yves, Torbey, Patrick, Gilardi-Hebenstreit, Pascale, Crollius, Hugues Roest
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049698/
https://ncbi.nlm.nih.gov/pubmed/31943068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1199
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