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Selective phytochemicals targeting pancreatic stellate cells as new anti-fibrotic agents for chronic pancreatitis and pancreatic cancer

Activated pancreatic stellate cells (PSCs) have been widely accepted as a key precursor of excessive pancreatic fibrosis, which is a crucial hallmark of chronic pancreatitis (CP) and its formidable associated disease, pancreatic cancer (PC). Hence, anti-fibrotic therapy has been identified as a nove...

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Dettagli Bibliografici
Pubblicato in:Acta Pharm Sin B
Autori principali: Ramakrishnan, Puvanesswaray, Loh, Wei Mee, Gopinath, Subash C.B., Bonam, Srinivasa Reddy, Fareez, Ismail M., Mac Guad, Rhanye, Sim, Maw Shin, Wu, Yuan Seng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049637/
https://ncbi.nlm.nih.gov/pubmed/32140388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.11.008
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