Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent

Ischemic stroke is a severe disorder resulting from acute cerebral thrombosis. Here we demonstrated that post-ischemic treatment with ciclopirox olamine (CPX), a potent antifungal clinical drug, alleviated brain infarction, neurological deficits and brain edema in a classic rat model of ischemic str...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Feng, Hongxuan, Hu, Linghao, Zhu, Hongwen, Tao, Lingxue, Wu, Lei, Zhao, Qinyuan, Gao, Yemi, Gong, Qi, Mao, Fei, Li, Xiaokang, Zhou, Hu, Li, Jian, Zhang, Haiyan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049605/
https://ncbi.nlm.nih.gov/pubmed/32140390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.08.002
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