Highly sensitive and specific in situ hybridization assay for quantification of SOX11 mRNA in mantle cell lymphoma reveals association of TP53 mutations with negative and low SOX11 expression

SOX11 is a valuable marker to identify biologically and clinically relevant groups of mantle cell lymphoma such as cyclin D1 negative and leukemic non-nodal mantle cell lymphoma (MCL). We aimed to establish a sensitive in situ hybridization analysis of SOX11 mRNA allowing its quantification within t...

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Publicat a:Haematologica
Autors principals: Federmann, Birgit, Frauenfeld, Leonie, Pertsch, Helga, Borgmann, Vanessa, Steinhilber, Julia, Bonzheim, Irina, Fend, Falko, Quintanilla-Martinez, Leticia
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049372/
https://ncbi.nlm.nih.gov/pubmed/31296581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.219543
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