Fbxo9 functions downstream of Sox10 to determine neuron-glial fate choice in the dorsal root ganglia through Neurog2 destabilization

The transcription factor Sox10 is a key regulator in the fate determination of a subpopulation of multipotent trunk neural crest (NC) progenitors toward glial cells instead of sensory neurons in the dorsal root ganglia (DRG). However, the mechanism by which Sox10 regulates glial cell fate commitment...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Liu, Jessica Aijia, Tai, Andrew, Hong, Jialin, Cheung, May Pui Lai, Sham, Mai Har, Cheah, Kathryn S. E., Cheung, Chi Wai, Cheung, Martin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2020
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049171/
https://ncbi.nlm.nih.gov/pubmed/32029586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916164117
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