Φορτώνει......
Erk1/2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates
Anthrax lethal toxin (LT) is a protease virulence factor produced by Bacillus anthracis that is required for its pathogenicity. LT treatment causes a rapid degradation of c-Jun protein that follows inactivation of the MEK1/2-Erk1/2 signaling pathway. Here we identify COP1 as the ubiquitin E3 ligase...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Proc Natl Acad Sci U S A |
|---|---|
| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2020
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7049164/ https://ncbi.nlm.nih.gov/pubmed/32041890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913698117 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|