The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition

Endothelial cells play an important role in maintenance of the vascular system and the repair after injury. Under proinflammatory conditions, endothelial cells can acquire a mesenchymal phenotype by a process named endothelial-to-mesenchymal transition (EndMT), which affects the functional propertie...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Glaser, Simone F., Heumüller, Andreas W., Tombor, Lukas, Hofmann, Patrick, Muhly-Reinholz, Marion, Fischer, Ariane, Günther, Stefan, Kokot, Karoline E., Okada, Hitoshi, Hassel, David, Kumar, Sandeep, Jo, Hanjoong, Boon, Reinier A., Abplanalp, Wesley, John, David, Boeckel, Jes-Niels, Dimmeler, Stefanie
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049147/
https://ncbi.nlm.nih.gov/pubmed/32034099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913481117
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