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Tumor slice culture as a biologic surrogate of human cancer

BACKGROUND: The tumor microenvironment (TME) is critical to every aspect of cancer biology. Organotypic tumor slice cultures (TSCs) preserve the original TME and have demonstrated utility in predicting drug sensitivity, but the association between clinicopathologic parameters and in vitro TSC behavi...

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Bibliografiske detaljer
Udgivet i:Ann Transl Med
Main Authors: Kenerson, Heidi L., Sullivan, Kevin M., Seo, Yongwoo D., Stadeli, Kathryn M., Ussakli, Cigdem, Yan, Xiaowei, Lausted, Chris, Pillarisetty, Venu G., Park, James O., Riehle, Kimberly J., Yeh, Matthew, Tian, Qiang, Yeung, Raymond S.
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049013/
https://ncbi.nlm.nih.gov/pubmed/32175407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.12.88
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