Nrf2 positively regulates autophagy antioxidant response in human bronchial epithelial cells exposed to diesel exhaust particles

Diesel exhaust particles (DEP) are known to generate reactive oxygen species in the respiratory system, triggering cells to activate antioxidant defence mechanisms, such as Keap1-Nrf2 signalling and autophagy. The aim of this study was to investigate the relationship between the Keap1-Nrf2 signallin...

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Pubblicato in:Sci Rep
Autori principali: Frias, Daniela Perroni, Gomes, Raquel Labiapari Nunes, Yoshizaki, Kelly, Carvalho-Oliveira, Regiani, Matsuda, Monique, Junqueira, Mara de Souza, Teodoro, Walcy Rosolia, Vasconcellos, Pérola de Castro, Pereira, Daniela Cristina de Almeida, Conceição, Paulo Roberto da, Saldiva, Paulo Hilário Nascimento, Mauad, Thais, Macchione, Mariangela
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048799/
https://ncbi.nlm.nih.gov/pubmed/32111854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59930-3
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