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The role of ubiquitination in tumorigenesis and targeted drug discovery

Ubiquitination, an important type of protein posttranslational modification (PTM), plays a crucial role in controlling substrate degradation and subsequently mediates the “quantity” and “quality” of various proteins, serving to ensure cell homeostasis and guarantee life activities. The regulation of...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Deng, Lu, Meng, Tong, Chen, Lei, Wei, Wenyi, Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048745/
https://ncbi.nlm.nih.gov/pubmed/32296023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0107-0
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