Longitudinal DNA methylation differences precede type 1 diabetes

DNA methylation may be involved in development of type 1 diabetes (T1D), but previous epigenome-wide association studies were conducted among cases with clinically diagnosed diabetes. Using multiple pre-disease peripheral blood samples on the Illumina 450 K and EPIC platforms, we investigated longit...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Johnson, Randi K., Vanderlinden, Lauren A., Dong, Fran, Carry, Patrick M., Seifert, Jennifer, Waugh, Kathleen, Shorrosh, Hanan, Fingerlin, Tasha, Frohnert, Brigitte I., Yang, Ivana V., Kechris, Katerina, Rewers, Marian, Norris, Jill M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048736/
https://ncbi.nlm.nih.gov/pubmed/32111940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60758-0
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