The association of miR34b/c and TP53 gene polymorphisms with Wilms tumor risk in Chinese children

Wilms tumor is the most common pediatric malignancy in the kidney. The miR34b/c is a downstream target gene of the transcription factor p53. The important role of TP53 mutations, the methylation of miR34b/c, and the interaction between these two molecules in tumorigenesis have been well documented....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Wang, Juxiang, Lou, Susu, Huang, Xiaokai, Mo, Yixiao, Wang, Zhen, Zhu, Jinhong, Tian, Xiaoqian, Shi, Jiandong, Zhou, Haixia, He, Jing, Ruan, Jichen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2020
Schlagworte:
Diagnostics & Biomarkers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048686/
https://ncbi.nlm.nih.gov/pubmed/32083300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20194202
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