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Measuring Glymphatic Flow in Man Using Quantitative Contrast-Enhanced MRI

On the basis of animal models, glymphatic flow disruption is hypothesized to be a factor in the development of Alzheimer's disease. We report the first quantitative study of glymphatic flow in man, combining intrathecal administration of gadobutrol with serial T1 mapping to produce contrast con...

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Detalles Bibliográficos
Publicado en:AJNR Am J Neuroradiol
Main Authors: Watts, R., Steinklein, J.M., Waldman, L., Zhou, X., Filippi, C.G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Neuroradiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048502/
https://ncbi.nlm.nih.gov/pubmed/30679221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3174/ajnr.A5931
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