Interaction between HuR and circPABPN1 Modulates Autophagy in the Intestinal Epithelium by Altering ATG16L1 Translation

Intestinal epithelial autophagy is crucial for host defense against invasive pathogens, and defects in this process occur frequently in patients with inflammatory bowel disease (IBD) and other mucosal disorders, but the exact mechanism that activates autophagy is poorly defined. Here, we investigate...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Li, Xiao-Xue, Xiao, Lan, Chung, Hee Kyoung, Ma, Xiang-Xue, Liu, Xiangzheng, Song, Jia-Le, Jin, Cindy Z., Rao, Jaladanki N., Gorospe, Myriam, Wang, Jian-Ying
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048268/
https://ncbi.nlm.nih.gov/pubmed/31932481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00492-19
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