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Effects of sample age on data quality from targeted sequencing of museum specimens: what are we capturing in time?

BACKGROUND: Next generation sequencing (NGS) can recover DNA data from valuable extant and extinct museum specimens. However, archived or preserved DNA is difficult to sequence because of its fragmented, damaged nature, such that the most successful NGS methods for preserved specimens remain sub-opt...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteur principal: McGaughran, Angela
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048091/
https://ncbi.nlm.nih.gov/pubmed/32111157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-6594-0
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