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The in vivo role of Rev1 in mutagenesis and carcinogenesis
Translesion synthesis (TLS) is an error-prone pathway required to overcome replication blockage by DNA damage. Aberrant activation of TLS has been suggested to play a role in tumorigenesis by promoting genetic mutations. However, the precise molecular mechanisms underlying TLS-mediated tumorigenesis...
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| Veröffentlicht in: | Genes Environ |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7048032/ https://ncbi.nlm.nih.gov/pubmed/32161626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-020-0148-1 |
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