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Non-enzymatic activity of the α-tubulin acetyltransferase αTAT1 limits synaptic bouton growth in neurons

Neuronal axons terminate as synaptic boutons that form stable yet plastic connections with their targets. Synaptic bouton development relies on an underlying network of both long-lived and dynamic microtubules that provide structural stability for the boutons while also allowing for their growth and...

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Vydáno v:Curr Biol
Hlavní autoři: Coombes, Courtney E., Saunders, Harriet A. J., Mannava, Anirudh G., Johnson-Schlitz, Dena M., Reid, Taylor A., Parmar, Sneha, McClellan, Mark, Yan, Connie, Rogers, Stephen L., Parrish, Jay Z., Wagenbach, Michael, Wordeman, Linda, Wildonger, Jill, Gardner, Melissa K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047862/
https://ncbi.nlm.nih.gov/pubmed/31928876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.12.022
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