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SPT20 Regulates the Hog1-MAPK Pathway and Is Involved in Candida albicans Response to Hyperosmotic Stress

Candida albicans is the most common fungal pathogen and relies on the Hog1-MAPK pathway to resist osmotic stress posed by the environment or during host invasions. Here, we investigated the role of SPT20 in response to osmotic stress. Testing a C. albicans spt20Δ/Δ mutant, we found it was sensitive...

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Publicat a:Front Microbiol
Autors principals: Wang, Lianfang, Chen, Ruilan, Weng, Qiuting, Lin, Shaoming, Wang, Huijun, Li, Li, Fuchs, Beth Burgwyn, Tan, Xiaojiang, Mylonakis, Eleftherios
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047840/
https://ncbi.nlm.nih.gov/pubmed/32153525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00213
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