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IgE contributes to atherosclerosis and obesity by affecting macrophage polarization, macrophage protein network, and foam cell formation
OBJECTIVE: By binding to its high affinity receptor FcεR1, IgE activates mast cells, macrophages, and other inflammatory and vascular cells. Recent studies support an essential role of IgE in cardiometabolic diseases. Plasma IgE level is an independent predictor of human coronary heart disease. Yet,...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7047522/ https://ncbi.nlm.nih.gov/pubmed/31996021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.313744 |
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