METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST

BACKGROUND: N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is very limited. We designed this study to investigate the role of m6A in CRC. METHODS: Expression level of METTL14 was extracted from pu...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Yang, Xiao, Zhang, Sen, He, Changyu, Xue, Pei, Zhang, Luyang, He, Zirui, Zang, Lu, Feng, Bo, Sun, Jing, Zheng, Minhua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047419/
https://ncbi.nlm.nih.gov/pubmed/32111213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-1146-4
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