METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST

BACKGROUND: N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is very limited. We designed this study to investigate the role of m6A in CRC. METHODS: Expression level of METTL14 was extracted from pu...

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Publicat a:Mol Cancer
Autors principals: Yang, Xiao, Zhang, Sen, He, Changyu, Xue, Pei, Zhang, Luyang, He, Zirui, Zang, Lu, Feng, Bo, Sun, Jing, Zheng, Minhua
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047419/
https://ncbi.nlm.nih.gov/pubmed/32111213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-1146-4
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