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METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST

BACKGROUND: N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is very limited. We designed this study to investigate the role of m6A in CRC. METHODS: Expression level of METTL14 was extracted from pu...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer
Hauptverfasser: Yang, Xiao, Zhang, Sen, He, Changyu, Xue, Pei, Zhang, Luyang, He, Zirui, Zang, Lu, Feng, Bo, Sun, Jing, Zheng, Minhua
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047419/
https://ncbi.nlm.nih.gov/pubmed/32111213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-1146-4
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