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Systematic identification of CDC34 that functions to stabilize EGFR and promote lung carcinogenesis
BACKGROUND: How the oncoprotein epidermal growth factor receptor (EGFR) evades proteolytic degradation and accumulates in non-small cell lung cancer (NSCLC) remains unclear, and ubiquitin pathway genes (UPGs) that are critical to NSCLC needs to be systematically identified. METHODS: A total of 696 U...
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| Publicado no: | EBioMedicine |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7047192/ https://ncbi.nlm.nih.gov/pubmed/32114396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102689 |
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