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Use of LUCS (Light-Up Cell System) as an alternative live cell method to predict human acute oral toxicity
LUCS (Light-Up Cell System) is a new live cell test that allows assessment of a cell’s homeostasis and its alteration by a toxic agent. To evaluate the effectiveness of LUCS as an alternative test method for acute oral toxicity, we compared EC(50)s determined in HepG2 cells treated with 53 chemicals...
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| Publicado no: | Toxicol Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7047139/ https://ncbi.nlm.nih.gov/pubmed/32140424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2020.02.010 |
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