Long-Term Toxicity Study of Topical Administration of a Highly-Stable rh-aFGF Carbomer 940 Hydrogel in a Rabbit Skin Wound Model

We developed a highly stable recombinant human acidic fibroblast growth factor (rh-aFGF) carbomer 940 hydrogel for wound healing. This study aimed to reveal toxicity target organs and the toxicity dose-response in the long-term administration of rh-aFGF carbomer 940 hydrogel in a rabbit skin wound m...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Zhang, Li, Huang, Tongzhou, Bi, Jianing, Zheng, Yingying, Lu, Chao, Hui, Qi, Wang, Xiaojie, Lin, Xiaohua
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046797/
https://ncbi.nlm.nih.gov/pubmed/32153396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00058
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