Delivering Crocetin across the Blood-Brain Barrier by Using γ-Cyclodextrin to Treat Alzheimer’s Disease

Crocetin (CRT) has shown various neuroprotective effects such as antioxidant activities and the inhibition of amyloid β fibril formation, and thus is a potential therapeutic candidate for Alzheimer’s disease (AD). However, poor water solubility and bioavailability are the major obstacles in formulat...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Wong, Ka Hong, Xie, Yuning, Huang, Xiao, Kadota, Kazunori, Yao, Xin-Sheng, Yu, Yang, Chen, Xiaoyu, Lu, Aiping, Yang, Zhijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046745/
https://ncbi.nlm.nih.gov/pubmed/32107408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60293-y
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