Association of MSH2 Expression With Tumor Mutational Burden and the Immune Microenvironment in Lung Adenocarcinoma

Immune checkpoint blockade (ICB) therapies that target programmed cell death 1 (PD1) and PD1 ligand 1 (PDL1) have demonstrated promising benefits in lung adenocarcinoma (LUAD), and tumor mutational burden (TMB) is the most robust biomarker associated with the efficacy of PD-1-PD-L1 axis blockade in...

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Udgivet i:Front Oncol
Main Authors: Jia, Mingming, Yao, Linli, Yang, Qin, Chi, Tian
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046689/
https://ncbi.nlm.nih.gov/pubmed/32154170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00168
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