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Unveiling the Impact of Morphine on Tamoxifen Metabolism in Mice in vivo
Background: Tamoxifen is used to treat breast cancer and cancer recurrences. After administration, tamoxifen is converted into two more potent antitumor compounds, 4OH-tamoxifen and endoxifen by the CYP3A4/5 and 2D6 enzymes in human. These active compounds are inactivated by the same UDP-glucuronosy...
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| Publicado no: | Front Oncol |
|---|---|
| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7046683/ https://ncbi.nlm.nih.gov/pubmed/32154159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00025 |
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