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Whole embryo culture, transcriptomics and RNA interference identify TBX1 and FGF11 as novel regulators of limb development in the mouse

Identifying genes involved in vertebrate developmental processes and characterizing this involvement are daunting tasks, especially in the mouse where viviparity complicates investigations. Attempting to devise a streamlined approach for this type of study we focused on limb development. We cultured...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Tejedor, Gautier, Laplace-Builhé, Béryl, Luz-Crawford, Patricia, Assou, Said, Barthelaix, Audrey, Mathieu, Marc, Kissa, Karima, Jorgensen, Christian, Collignon, Jérôme, Chuchana, Paul, Djouad, Farida
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046665/
https://ncbi.nlm.nih.gov/pubmed/32107392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60217-w
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