Nontoxic concentration of ochratoxin A decreases the dosage of cyclosporine A to induce chronic nephropathy model via autophagy mediated by toll-like receptor 4

Cyclosporine A (CsA) extracted from the products of fungal fermentation is used to develop a chronic nephropathy model. However, it has numerous side effects. Ochratoxin A (OTA) is a mycotoxin that induces renal injury. We developed a chronic nephropathy model to lessen the side effects of CsA by ad...

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Udgivet i:Cell Death Dis
Main Authors: Hou, Lili, Le, Guannan, Lin, Ziman, Qian, Gang, Gan, Fang, Gu, Cong, Jiang, Shuai, Mu, Jiaxin, Ge, Lei, Huang, Kehe
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046648/
https://ncbi.nlm.nih.gov/pubmed/32108135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2353-z
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