Genetic Deletion of Socs3 in Smooth Muscle Cells Ameliorates Aortic Dissection in Mice

Aortic dissection (AD) is the acute destruction of aortic wall and is reportedly induced by inflammatory response. Here we investigated the role of smooth muscle Socs3 (a negative regulator of Janus kinases/signal transducer and activator of transcription signaling) in AD pathogenesis using a mouse...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Hirakata, Saki, Aoki, Hiroki, Ohno-Urabe, Satoko, Nishihara, Michihide, Furusho, Aya, Nishida, Norifumi, Ito, Sohei, Hayashi, Makiko, Yasukawa, Hideo, Imaizumi, Tsutomu, Hiromatsu, Sinichi, Tanaka, Hiroyuki, Fukumoto, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
PRECLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046542/
https://ncbi.nlm.nih.gov/pubmed/32140621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.10.010
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